Steroids and COVID-19!!!
STEROIDS
Most of the people in the world are medicated with
steroids for different types of chronic diseases. A certain type of steroid
is found to be more susceptible to the viral infections such as SARS and as
in the recent days "COVID -19".
Classes of Steroids
The classes of steroids are :
1. Progestins
2. Androgens
3. Estrogens and
4. Corticoids
Out of these types of steroids, Glucocorticoids are the
drugs that are more susceptible to viral infections which are more likely to
contract COVID-19, if they are affected, they are likely to show severe
symptoms.
Glucocorticoids are a class of corticosteroids, which are a class
of steroid hormones.
Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that
is present in almost every vertebrate cell. The name "glucocorticoid" is a portmanteau (glucose + cortex + steroid)
and is composed from its role in regulation of glucose metabolism, synthesis in the adrenal
cortex, and its steroidal structure. This can be produced by the body
itself. But in cases, it cannot be secreted due to some chronic problems. For
example, Adrenal Insufficiency, Inflammatory diseases like inflammatory bowel
disease, asthma, obstructive pulmonary disease and so on.
Glucocorticoids
have both pros and cons. It is the condition of Immuno deficiency which is
these steroids suppress the immune system. And the drug taking person cannot
fight off the infection once they are affected. They are more likely to show
severe responses as their immune system cannot resist or fight it.
For the
patients undertaking glucocorticoid, if they are affected with the disease,
they should immediately double their dose until the fever subsides. If the
symptoms like diarrhea or vomiting occur at extreme stages, they should
contact their doctors who might decide to prescribe Parenteral Glucocorticoid
Therapy.
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